Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9938520 | 0.91 | CCR2 (0.64) | CCR2 | |
| SCHEMBL16467090 | 0.83 | CCR2 (0.65) | CCR2 | |
| SCHEMBL307570 | 0.80 | CCR2 (0.67) | CCR2 | |
| SCHEMBL9932289 | 0.80 | CCR2 (0.64) | CCR2 | |
| SCHEMBL9934855 | 0.79 | CCR2 (0.72) | CCR2 | |
| SCHEMBL10796134 | 0.79 | CCR2 (0.71) | CCR2 | |
| SCHEMBL31704002 | 0.79 | CCR2 (0.78) | CCR2 | |
| SCHEMBL9932896 | 0.78 | CCR2 (0.61) | CCR2 | |
| SCHEMBL9933283 | 0.78 | CCR2 (0.70) | CCR2 | |
| SCHEMBL9934800 | 0.78 | CCR2 (0.82) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651957-B1 | PHOSPHOROUS DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2015-02-18 | — | — | EP | claimed |
| US-8518913-B2 | Phosphorous derivatives as chemokine receptor modulators | ALLERGAN, INC. (US) | 2013-08-27 | — | — | US | claimed |
| EP-2651957-B1 | PHOSPHOROUS DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2015-02-18 | — | — | EP | disclosed |
| EP-2651957-A1 | PHOSPHOROUS DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | Allergan, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082568-A1 | PHOSPHOROUS DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2012-06-21 | — | — | WO | disclosed |