Rimsulfuron

Rimsulfuron

SCHEMBL9938830

CCS(=O)(=O)c1cccnc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1.CP(=O)(O)CCC(N)C(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
MAPT P10636 3/20 0.38
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
CDK1 P06493 1/20 0.36
GRM8 O00222 3/20 0.36
GRM4 Q14833 3/20 0.36
KMT2A Q03164 1/20 0.35
GRM6 O15303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flazasulfuron SCHEMBL19463587 0.87 GAA (0.42) GAAMAPTTP53GLACDK1
Nicosulfuron SCHEMBL19463673 0.86 CDK1 (0.46) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL27828098 0.86 GAA (0.54) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL37660 0.86 GAA (0.54) GAAMAPTTP53GLACDK1
Trifloxysulfuron SCHEMBL19464014 0.85 GAA (0.43) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL7578982 0.85 MEN1 (0.37) GAAGRM8GRM4KMT2AGRM6
Rimsulfuron SCHEMBL15524978 0.85 GAA (0.53) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL15524977 0.85 GAA (0.53) GAAMAPTTP53GLACDK1
Rimsulfuron SCHEMBL7577414 0.82 GRM8 (0.32) GAAGRM8GRM4GRM6
Rimsulfuron SCHEMBL7582269 0.82 TDP1 (0.44) GRM8GRM4GRM6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3442962-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS Syngenta Participations AG (CH) 2019-02-20 EP disclosed
WO-2017178582-A1 HERBICIDAL PYRIDAZINONE COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2017-10-19 WO disclosed
WO-2012082542-A2 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO disclosed