Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HK2 | P52789 | 5/20 | 0.45 |
| ▸ | HK1 | P19367 | 4/20 | 0.45 |
| ▸ | PYGB | P11216 | 6/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10004142 | 1.00 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL9938837 | 1.00 | KDM4E (0.49) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL14582934 | 0.83 | KDM4E (0.55) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL15966251 | 0.81 | PYGB (0.66) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL22166026 | 0.81 | PYGB (0.66) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL23315864 | 0.81 | KDM4E (0.52) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL14653772 | 0.81 | PYGB (0.66) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL21401312 | 0.81 | KDM4E (0.52) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL16129445 | 0.81 | KDM4E (0.52) | KDM4ELMNACYP2D6CYP2C19HK2 | |
| SCHEMBL5158214 | 0.81 | PYGB (0.66) | KDM4ELMNACYP2D6CYP2C19HK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012103990-A1 | PHOSPHORAMIDATES OF MONOSACCHARIDES | BIOIBERICA, S.A. (ES) | 2012-08-09 | — | — | WO | disclosed |
| EP-2471802-A1 | Phosphoramidates of monosaccharides | Bioiberica, S.A. (ES) | 2012-07-04 | — | — | EP | disclosed |
| WO-2012083145-A1 | GLUCOSAMINE DERIVATIVES | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2012-06-21 | — | — | WO | disclosed |