Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3840247 | 0.86 | HRH3 (0.42) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL3841613 | 0.85 | HRH3 (0.41) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL3846855 | 0.85 | HRH3 (0.41) | HRH3ALDH1A1MAPK1PARP1PKM | |
| Hydrochloric Acid SCHEMBL28183399 | 0.85 | HRH3 (0.41) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL27345731 | 0.81 | HRH3 (0.39) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL152356 | 0.81 | HRH3 (0.39) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL27934300 | 0.81 | KCNH2 (0.48) | HRH3ALDH1A1PKMHPGDGPR84 | |
| SCHEMBL28272718 | 0.81 | KCNH2 (0.48) | HRH3ALDH1A1PKMHPGDGPR84 | |
| SCHEMBL3841860 | 0.81 | HRH3 (0.41) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL1063754 | 0.81 | KCNH2 (0.47) | ALDH1A1PKMHPGDGPR84KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104955332-A | Method for controlling arthropod pest | SUMITOMO CHEMICAL CO | 2015-09-30 | — | — | CN | disclosed |
| WO-2012082574-A1 | MEMBRANE LYTIC POLY(AMIDO AMINE) POLYMERS FOR THE DELIVERY OF OLIGONUCLEOTIDES | MERCK SHARP & DOHME CORP. (US) | 2012-06-21 | — | — | WO | disclosed |