Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758020 | 0.92 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL4134073 | 0.92 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL27983100 | 0.92 | ALDH1A1 (0.44) | ALDH1A1PKMHPGDKCNH2GPR84 | |
| SCHEMBL3840247 | 0.90 | HRH3 (0.42) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL3841613 | 0.88 | HRH3 (0.41) | HRH3ALDH1A1MAPK1PARP1PKM | |
| Hydrochloric Acid SCHEMBL28183399 | 0.88 | HRH3 (0.41) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL3697323 | 0.88 | GLA (0.33) | HRH3NOS2 | |
| SCHEMBL9939121 | 0.85 | HRH3 (0.39) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL152356 | 0.85 | HRH3 (0.39) | HRH3ALDH1A1MAPK1PARP1PKM | |
| SCHEMBL28272718 | 0.85 | KCNH2 (0.48) | HRH3ALDH1A1PKMHPGDKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024219430-A1 | LATENT CURING AGENT AND ONE-PACK EPOXY RESIN COMPOSITION | 株式会社T&K TOKA | 2024-10-24 | — | — | WO | disclosed |
| CN-108383135-A | A kind of ECNU-13 molecular sieves of topological structure and its preparation and application | 华东师范大学 | 2018-08-10 | — | — | CN | disclosed |
| US-9029449-B2 | Polymeric composition comprising metal alkoxide condensation product, organic silane compound and boron compound | NITTO BOSEKI CO., LTD. (JP) | 2015-05-12 | — | — | US | disclosed |
| EP-2072582-B1 | POLYMERIC COMPOSITION COMPRISING METAL ALKOXIDE CONDENSATION PRODUCT, ORGANIC SILANE COMPOUND AND BORON COMPOUND | NITTO BOSEKI CO LTD (JP) | 2011-12-07 | — | — | EP | disclosed |
| CN-101522809-B | Polymer composition containing metal alkoxide condensation product, organosilane compound and boron compound | NITTO BOSEKI CO LTD | 2011-10-26 | — | — | CN | disclosed |
| US-7902373-B2 | asthma; for treating prostaglandin D2 mediated diseases; e.g. 6-(3-fluorophenyl)-N-[1-(1-methyl-1H-tetrazol-5-yl)piperidin-4-yl]nicotinamide | PFIZER INC (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090252970-A1 | POLYMERIC COMPOSITION COMPRISING METAL ALKOXIDE CONDENSATION PRODUCT, ORGANIC SILANE COMPOUND AND BORON COMPOUND | NITTO BOSEKI CO., LTD. (JP) | 2009-10-08 | — | — | US | disclosed |
| CN-101522809-A | Polymer composition containing metal alkoxide condensation product, organosilane compound and boron compound | NITTO BOSEKI CO LTD (JP) | 2009-09-02 | — | — | CN | disclosed |
| EP-2072582-A1 | POLYMERIC COMPOSITION COMPRISING METAL ALKOXIDE CONDENSATION PRODUCT, ORGANIC SILANE COMPOUND AND BORON COMPOUND | Nitto Boseki CO., LTD. (JP) | 2009-06-24 | — | — | EP | disclosed |
| WO-2008075172-A2 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080146569-A1 | Nicotinamide Derivatives | PFIZER INC. | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146569-A1 | Nicotinamide Derivatives | NNT, NAMPT, NADK | HRH3 707/4885ALDH1A1 148/4885MAPK1 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.