Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.53 |
| ▸ | SHBG | P04278 | 4/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115613 | 0.83 | ABL1 (0.70) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL1115615 | 0.83 | ABL1 (0.70) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL5445469 | 0.83 | ABL1 (0.70) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL6448971 | 0.83 | ABL1 (0.70) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL6881931 | 0.83 | ABL1 (0.70) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL6876271 | 0.83 | ABL1 (0.70) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL14874852 | 0.82 | AR (0.70) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL1419433 | 0.82 | ABL1 (0.49) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL1418612 | 0.82 | ABL1 (0.49) | CYP19A1SHBGNR3C1PGRSERPINA6 | |
| SCHEMBL1418610 | 0.82 | ABL1 (0.49) | CYP19A1SHBGNR3C1PGRSERPINA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2667876-A2 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | Harbor BioSciences, Inc. (US) | 2013-12-04 | — | — | EP | disclosed |
| WO-2012083090-A2 | METHODS AND COMPOUNDS FOR PREPARING 3ALPHA-OXYGEN SUBSTITUTED STEROIDS | HARBOR BIOSCIENCES, INC. (US) | 2012-06-21 | — | — | WO | disclosed |