Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.70 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.70 |
| ▸ | SHBG | P04278 | 4/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.53 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6881931 | 1.00 | ABL1 (0.70) | ABL1RIN1SHBGGPBAR1LMNA | |
| SCHEMBL6876271 | 1.00 | ABL1 (0.70) | ABL1RIN1SHBGGPBAR1LMNA | |
| SCHEMBL1115613 | 1.00 | ABL1 (0.70) | ABL1RIN1SHBGGPBAR1LMNA | |
| SCHEMBL1115615 | 1.00 | ABL1 (0.70) | ABL1RIN1SHBGGPBAR1LMNA | |
| SCHEMBL5445469 | 1.00 | ABL1 (0.70) | ABL1RIN1SHBGGPBAR1LMNA | |
| SCHEMBL18508098 | 0.84 | ABL1 (0.65) | ABL1RIN1GPBAR1LMNACYP3A4 | |
| SCHEMBL17303242 | 0.84 | ABL1 (0.65) | ABL1RIN1GPBAR1LMNACYP3A4 | |
| SCHEMBL19302477 | 0.84 | ABL1 (0.65) | ABL1RIN1GPBAR1LMNACYP3A4 | |
| SCHEMBL9939124 | 0.83 | CYP19A1 (0.53) | ABL1RIN1SHBGGPBAR1SERPINA6 | |
| SCHEMBL7192083 | 0.83 | G6PD (0.67) | ABL1RIN1SHBGGPBAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050192262-A1 | Treatment of tumours | HAGSTROM, TOMAS (SE) | 2005-09-01 | — | — | US | claimed |
| EP-1379542-A2 | TREATMENT OF TUMOURS | Hagström, Tomas (SE) | 2004-01-14 | — | — | EP | claimed |
| WO-2002072003-A2 | USE OF STEROID DERIVATIVES FOR THE TREATMENT OF A BENIGHN AND/OR MALIGNANT TUMOUR | HAGSTROEM TOMAS (SE) | 2002-09-19 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192262-A1 | Treatment of tumours | SULT2A1, SULT1A1, HSD17B11 | ABL1 3893/4885RIN1 4759/4885SHBG 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.