Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939860 | 0.95 | PTGES (0.67) | PTGES | |
| SCHEMBL9939840 | 0.94 | PTGES (0.66) | PTGES | |
| SCHEMBL9939900 | 0.93 | PTGES (0.65) | PTGES | |
| SCHEMBL9939838 | 0.93 | PTGES (0.67) | PTGES | |
| SCHEMBL9939929 | 0.90 | PTGES (0.64) | PTGES | |
| SCHEMBL9939915 | 0.90 | PTGES (0.64) | PTGES | |
| SCHEMBL9939930 | 0.90 | PTGES (0.64) | PTGES | |
| SCHEMBL9939904 | 0.90 | PTGES (0.68) | PTGES | |
| SCHEMBL9939908 | 0.90 | PTGES (0.63) | PTGES | |
| SCHEMBL9939828 | 0.89 | PTGES (0.80) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649052-B1 | 2-AMINOBENZIMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INT (DE) | 2014-10-22 | — | — | EP | disclosed |
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |