Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 11/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939820 | 0.89 | PTGES (0.44) | ENPP2OPRL1KCNH2PTGESOPRK1 | |
| SCHEMBL9939992 | 0.83 | PTGES (0.37) | PTGES | |
| SCHEMBL9939985 | 0.81 | PTGES (0.45) | OPRL1KCNH2PTGESOPRK1 | |
| SCHEMBL9939884 | 0.80 | OPRL1 (0.42) | OPRL1KCNH2PTGESOPRK1 | |
| SCHEMBL9939886 | 0.78 | PTGES (0.44) | OPRL1KCNH2PTGESOPRK1 | |
| SCHEMBL9939894 | 0.78 | PTGES (0.46) | OPRL1KCNH2PTGESOPRK1 | |
| SCHEMBL9940060 | 0.78 | PTGES (0.44) | PTGES | |
| SCHEMBL9899436 | 0.77 | OPRL1 (0.39) | OPRL1PTGES | |
| SCHEMBL9939818 | 0.77 | PTGES (0.44) | PTGES | |
| SCHEMBL9940004 | 0.75 | PTGES (0.46) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |