SCHEMBL9940403

SCHEMBL9940403

Cc1cc(C#N)cc(C(=O)N(C)N(C)C(=O)O)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.40
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
KMT2A Q03164 1/20 0.33
PKM P14618 1/20 0.33
NR3C1 P04150 1/20 0.32
MALT1 Q9UDY8 2/20 0.31
RIPK1 Q13546 1/20 0.31
SLC2A1 P11166 1/20 0.31
SLC2A2 P11168 1/20 0.31
SLC2A3 P11169 1/20 0.31
SLC2A4 P14672 1/20 0.31
GCK P35557 2/20 0.31
KCNH2 Q12809 2/20 0.31
PPARG P37231 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
JAK2 O60674 1/20 0.30
JAK1 P23458 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30978017 1.00 DHODH (0.40) DHODHPDE4APDE4BPDE4CPDE4D
SCHEMBL12527922 0.94 DHODH (0.40) DHODHPDE4APDE4BPDE4CPDE4D
SCHEMBL12559377 0.92 DHODH (0.39) DHODHPDE4APDE4BPDE4CPDE4D
SCHEMBL12528632 0.92 DHODH (0.41) DHODHPDE4APDE4BPDE4CPDE4D
SCHEMBL9986989 0.92 DHODH (0.38) DHODHPDE4APDE4BPDE4CPDE4D
SCHEMBL30978016 0.92 DHODH (0.38) DHODHPDE4APDE4BPDE4CPDE4D
SCHEMBL950665 0.91 DHODH (0.41) DHODHPDE4APDE4BPDE4CPDE4D
SCHEMBL13726746 0.91 DHODH (0.41) DHODHPDE4APDE4BPDE4CPDE4D
SCHEMBL2594967 0.90 DHODH (0.41) DHODHKMT2AMALT1
SCHEMBL30978015 0.90 DHODH (0.41) DHODHKMT2AMALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3010893-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2019-10-02 EP claimed
EP-3395171-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2018-10-31 EP claimed
EP-3010889-B1 ARYLSULFIDE AND ARYLSULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-10-03 EP claimed
EP-2793578-B1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2018-06-06 EP claimed
EP-3010893-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-04-27 EP claimed
EP-3010889-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience Aktiengesellschaft (DE) 2016-04-27 EP claimed
EP-2935267-A1 ARYL SULFIDE DERIVATIVES AND ARYL SULFOXIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES Bayer CropScience AG (DE) 2015-10-28 EP claimed
EP-2925148-A1 COMPOSITION COMPRISING BIOLOGICAL CONTROL AGENTS Bayer CropScience AG (DE) 2015-10-07 EP claimed
EP-2925142-A2 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE Bayer CropScience AG (DE) 2015-10-07 EP claimed
EP-2925144-A2 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE Bayer CropScience AG (DE) 2015-10-07 EP claimed
WO-2014086756-A1 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2014-06-12 WO claimed
WO-2014086758-A2 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2014-06-12 WO claimed
WO-2014086749-A2 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2014-06-12 WO claimed
WO-2014086750-A2 COMPOSITION COMPRISING A BIOLOGICAL CONTROL AGENT AND AN INSECTICIDE BAYER CROPSCIENCE AG (DE) 2014-06-12 WO claimed
EP-2651209-A2 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF Syngenta Participations AG (CH) 2013-10-23 EP claimed
EP-2606726-A1 N-Arylamidine-substituted trifluoroethylsulfide derivatives as acaricides and insecticides Bayer CropScience AG (DE) 2013-06-26 EP claimed
EP-2582242-A1 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDE AND ACARICIDE PROPERTIES Bayer Intellectual Property GmbH (DE) 2013-04-24 EP claimed
WO-2012082548-A2 SOYBEAN EVENT SYHT0H2 AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2012082542-A2 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
WO-2011157778-A1 ACTIVE SUBSTANCE COMBINATIONS WITH INSECTICIDE AND ACARICIDE PROPERTIES BAYER CROPSCIENCE AG (DE) 2011-12-22 WO claimed