SCHEMBL950665

SCHEMBL950665

Cc1cc(C#N)cc(C(=O)N(C)N)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.41
KMT2A Q03164 1/20 0.36
PKM P14618 1/20 0.35
SLC2A1 P11166 3/20 0.35
SLC2A3 P11169 3/20 0.35
SLC2A4 P14672 3/20 0.35
SLC2A2 P11168 1/20 0.35
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
KCNH2 Q12809 4/20 0.33
GCK P35557 3/20 0.33
PPARG P37231 1/20 0.33
JAK2 O60674 1/20 0.33
JAK1 P23458 1/20 0.33
TYK2 P29597 1/20 0.33
JAK3 P52333 1/20 0.33
MALT1 Q9UDY8 1/20 0.33
NR3C1 P04150 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12528632 0.94 DHODH (0.41) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL12559450 0.92 DHODH (0.41) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL951370 0.92 DHODH (0.40) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL13726746 0.91 DHODH (0.41) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL9940403 0.91 DHODH (0.40) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL12527922 0.91 DHODH (0.40) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL30978017 0.91 DHODH (0.40) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL31059983 0.91 DHODH (0.42) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL29377007 0.91 DHODH (0.42) DHODHKMT2APKMSLC2A1SLC2A3
SCHEMBL959387 0.91 DHODH (0.42) DHODHKMT2APKMSLC2A1SLC2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104883888-A Compositions comprising biological control agents and pesticides BAYER CROPSCIENCE AG 2015-09-02 CN disclosed
CN-104519742-A Compositions comprising biological control agents and pesticides BAYER CROP SCIENCE AG 2015-04-15 CN disclosed
CN-104507310-A Compositions comprising biological control agents and insecticides BAYER CROPSCIENCE AG 2015-04-08 CN disclosed
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME IKEGAMI HIROSHI 2011-03-24 US disclosed
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 US disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-22 US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 US disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099692-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC1, UQCRC2, Q6ZSR9 DHODH 277/4885KMT2A 1245/4885PKM 312/4885
US-20110071291-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME ACHE, H1-2, H1-0 DHODH 771/4885KMT2A 404/4885PKM 861/4885
US-20100137314-A1 HARMFUL ORGANISM CONTROL COMPOSITION UQCRC2, UQCRC1, UQCRB DHODH 558/4885KMT2A 1430/4885PKM 376/4885
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885KMT2A 1294/4885PKM 600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.