Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15552245 | 0.93 | — | — | |
| SCHEMBL16557133 | 0.93 | — | — | |
| SCHEMBL15552926 | 0.92 | — | — | |
| SCHEMBL18056530 | 0.91 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL9940383 | 0.90 | CYP3A4 (0.46) | CYP3A4 | |
| SCHEMBL16652470 | 0.90 | — | — | |
| SCHEMBL9974863 | 0.89 | CYP3A4 (0.49) | CYP3A4 | |
| SCHEMBL31069310 | 0.88 | CYP3A4 (0.44) | CYP3A4 | |
| SCHEMBL30703880 | 0.88 | — | — | |
| SCHEMBL28831275 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944638-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND US (IE) | 2018-04-17 | — | — | US | disclosed |
| US-9944638-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND US (IE) | 2018-04-17 | — | — | US | disclosed |
| US-20160237083-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-08-18 | — | — | US | disclosed |
| US-20160237083-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-08-18 | — | — | US | disclosed |
| US-9321768-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2016-04-26 | — | — | US | disclosed |
| US-9321768-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2016-04-26 | — | — | US | disclosed |
| US-9321768-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2016-04-26 | — | — | US | disclosed |
| EP-2651922-B1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-02-24 | — | — | EP | disclosed |
| EP-2651922-B1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2016-02-24 | — | — | EP | disclosed |
| US-20150073013-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2015-03-12 | — | — | US | disclosed |
| US-20150073013-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2015-03-12 | — | — | US | disclosed |
| US-8921560-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN R&D IRELAND (IE) | 2014-12-30 | — | — | US | disclosed |
| US-8921560-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN R&D IRELAND (IE) | 2014-12-30 | — | — | US | disclosed |
| US-8921560-B2 | Indoles as respiratory syncytial virus antiviral agents | JANSSEN R&D IRELAND (IE) | 2014-12-30 | — | — | US | disclosed |
| EP-2651922-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | Janssen R&D Ireland (IE) | 2013-10-23 | — | — | EP | disclosed |
| US-20130267555-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2013-10-10 | — | — | US | disclosed |
| US-20130267555-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2013-10-10 | — | — | US | disclosed |
| US-20130267555-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2013-10-10 | — | — | US | disclosed |
| WO-2012080447-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |
| WO-2012080447-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237083-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | IDO1, IDO2, INMT | CYP3A4 81/4885 |
| US-20150073013-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | IDO1, IDO2, INMT | CYP3A4 81/4885 |
| US-20130267555-A1 | INDOLES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | IDO1, IDO2, INMT | CYP3A4 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.