SCHEMBL9940698

SCHEMBL9940698

CS(=O)(=O)CCCn1c(Cn2c(=O)n(C3CC3)c3ccncc32)nc2cc(Br)ccc21

nearest known ligand 0.59

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.59
TNKS O95271 1/20 0.34
CTSS P25774 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30110668 1.00 CYP3A4 (0.59) CYP3A4TNKSCTSS
SCHEMBL17613271 0.90 CYP3A4 (0.59) CYP3A4CTSS
SCHEMBL29658105 0.90 CYP3A4 (0.59) CYP3A4CTSS
SCHEMBL31069427 0.89 CYP3A4 (0.57) CYP3A4
SCHEMBL15306210 0.87 CYP3A4 (0.60) CYP3A4TNKS
SCHEMBL9940383 0.86 CYP3A4 (0.46) CYP3A4
SCHEMBL9979857 0.86 CYP3A4 (0.62) CYP3A4TNKS
SCHEMBL17613266 0.85 CYP3A4 (0.61) CYP3A4TNKS
SCHEMBL15301176 0.84 CYP3A4 (0.56) CYP3A4TNKS
SCHEMBL16696084 0.83 CYP3A4 (0.53) CYP3A4CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085675-A1 CONJUGATES, COMPOSITIONS AND METHODS FOR TREATING RSV INFECTION NIEDRAUER MARY LYNN (US) 2025-04-24 WO disclosed
EP-4126023-A1 STABILIZED VACCINE COMPOSITIONS Janssen Vaccines & Prevention B.V. (NL) 2023-02-08 EP disclosed
CN-115461076-A Stabilized vaccine compositions 扬森疫苗与预防公司 2022-12-09 CN disclosed
WO-2021198413-A1 STABILIZED VACCINE COMPOSITIONS JANSSEN VACCINES & PREVENTION B.V. (NL) 2021-10-07 WO disclosed
EP-2651903-B1 BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS JANSSEN SCIENCES IRELAND UC (IE) 2016-03-23 EP disclosed
US-8865705-B2 Benzimidazole respiratory syncytial virus inhibitors JANSSEN R&D IRELAND (IE) 2014-10-21 US disclosed
EP-2651903-A1 BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS Janssen R&D Ireland (IE) 2013-10-23 EP disclosed
US-20130267508-A1 BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS JANSSEN R&D IRELAND (IE) 2013-10-10 US disclosed
WO-2012080446-A1 BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS JANSSEN R&D IRELAND (IE) 2012-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267508-A1 BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS SBDS, CHUK, HAT1 CYP3A4 34/4885TNKS 2070/4885CTSS 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.