Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 9/20 | 0.38 |
| ▸ | BACE1 | P56817 | 5/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9941216 | 0.74 | TBXA2R (0.37) | TBXA2R | |
| SCHEMBL9979854 | 0.71 | BACE1 (0.54) | TBXA2RBACE1NUDT1KDM4EALDH1A1 | |
| SCHEMBL9979855 | 0.70 | BACE1 (0.49) | TBXA2RBACE1NUDT1 | |
| SCHEMBL9940520 | 0.69 | CYP3A4 (0.45) | TBXA2RKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL15301119 | 0.69 | BACE1 (0.48) | TBXA2RBACE1NUDT1 | |
| SCHEMBL23100606 | 0.67 | MAPT (0.53) | TBXA2RBACE1NUDT1 | |
| SCHEMBL9940732 | 0.63 | CYP3A4 (0.46) | BACE1 | |
| SCHEMBL9979870 | 0.62 | BACE1 (0.36) | BACE1NUDT1 | |
| SCHEMBL23100601 | 0.61 | SMN1; SMN2 (0.43) | BACE1NUDT1KDM4EALDH1A1 | |
| SCHEMBL23100636 | 0.61 | BACE1 (0.63) | TBXA2RBACE1NUDT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651903-A1 | BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | Janssen R&D Ireland (IE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080446-A1 | BENZIMIDAZOLE RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | JANSSEN R&D IRELAND (IE) | 2012-06-21 | — | — | WO | disclosed |