Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 7/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14244005 | 0.87 | ALOX5AP (0.51) | ALOX5APABL1GSK3BDYRK1AWNT1 | |
| SCHEMBL9966224 | 0.77 | ALOX5AP (0.49) | ALOX5APABL1GSK3BDYRK1AIDO1 | |
| SCHEMBL9966483 | 0.73 | ALOX5AP (0.42) | ALOX5APALDH1A1IDO1 | |
| SCHEMBL14244265 | 0.73 | ALDH1A1 (0.54) | ALOX5APHDAC1ALDH1A1HTTIDO1 | |
| SCHEMBL9935698 | 0.72 | ALDH1A1 (0.47) | ALOX5APHDAC1ALDH1A1HTTIDO1 | |
| SCHEMBL9936886 | 0.72 | IDO1 (0.48) | ALOX5APHDAC1ALDH1A1HTTIDO1 | |
| SCHEMBL9966255 | 0.72 | ABL1 (0.43) | ALOX5APABL1ALDH1A1CTPS1 | |
| SCHEMBL9966521 | 0.72 | IDO1 (0.43) | ALOX5APHDAC1ALDH1A1HTTIDO1 | |
| SCHEMBL14325150 | 0.72 | HDAC1 (0.46) | ALOX5APHDAC1ALDH1A1HTTIDO1 | |
| SCHEMBL9936451 | 0.71 | IDO1 (0.45) | ALOX5APHDAC1ALDH1A1HTTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651930-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | Boehringer Ingelheim International GmbH (DE) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |