Sugi Predict

Sugi Predict / Compounds / SCHEMBL9943293

SCHEMBL9943293

SCHEMBL9943293

COc1cccc([C@@H](Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)[C@H](C)NC(=O)C2CCN(OC(=O)OC(C)(C)C)C2)c1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 20/20 0.67
▸ PGR P06401 4/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12965364 0.90 NR3C1 (0.68) NR3C1PGR
SCHEMBL833929 0.90 NR3C1 (0.68) NR3C1PGR
SCHEMBL833928 0.90 NR3C1 (0.68) NR3C1PGR
SCHEMBL851215 0.90 NR3C1 (0.68) NR3C1PGR
SCHEMBL836122 0.85 NR3C1 (0.78) NR3C1PGR
SCHEMBL836121 0.85 NR3C1 (0.78) NR3C1PGR
SCHEMBL836492 0.83 NR3C1 (0.68) NR3C1PGR
SCHEMBL836491 0.83 NR3C1 (0.68) NR3C1PGR
SCHEMBL836493 0.83 NR3C1 (0.68) NR3C1PGR
SCHEMBL850993 0.83 NR3C1 (0.81) NR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102169-B1 INDAZOLYL AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS ASTRAZENECA AB (SE) 2012-06-20 — — EP claimed