Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.50 |
| ▸ | SMO | Q99835 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9943272 | 0.81 | NR3C1 (0.57) | NR3C1SMOPGR | |
| SCHEMBL837680 | 0.78 | NR3C1 (0.58) | NR3C1PGR | |
| SCHEMBL837679 | 0.78 | NR3C1 (0.58) | NR3C1PGR | |
| SCHEMBL12804966 | 0.78 | NR3C1 (0.56) | NR3C1PGR | |
| SCHEMBL9943265 | 0.76 | NR3C1 (0.50) | NR3C1SMOPGR | |
| SCHEMBL837689 | 0.76 | NR3C1 (0.64) | NR3C1PGR | |
| SCHEMBL3806403 | 0.76 | NR3C1 (0.64) | NR3C1PGR | |
| SCHEMBL837690 | 0.76 | NR3C1 (0.64) | NR3C1PGR | |
| SCHEMBL833453 | 0.75 | NR3C1 (0.58) | NR3C1PGR | |
| SCHEMBL4226242 | 0.75 | NR3C1 (0.58) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102169-B1 | INDAZOLYL AMIDE DERIVATIVES FOR THE TREATMENT OF GLUCOCORTICOID RECEPTOR MEDIATED DISORDERS | ASTRAZENECA AB (SE) | 2012-06-20 | — | — | EP | disclosed |