Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SMOX | Q9NWM0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561249 | 0.83 | GAA (0.51) | GAAGFERMEN1KMT2ASMOX | |
| SCHEMBL8356823 | 0.79 | MEN1 (0.51) | GAAMAOAMEN1KMT2A | |
| SCHEMBL8351640 | 0.72 | MCL1 (0.52) | GAAGFERMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10561364 | 0.71 | MCL1 (0.51) | GAAGFERMEN1KMT2AMAPT | |
| SCHEMBL17742100 | 0.65 | GAA (0.61) | GAAGFERMAOASMOX | |
| SCHEMBL4338778 | 0.65 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL12845739 | 0.64 | GAA (0.70) | GAAGFERMEN1KMT2AMAPT | |
| SCHEMBL5227239 | 0.64 | GAA (0.50) | GAAGFERPOLBMEN1KMT2A | |
| SCHEMBL6744037 | 0.63 | GAA (1.00) | GAAGFERMEN1KMT2AMAPT | |
| SCHEMBL11537267 | 0.63 | KMT2A (0.65) | MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745041-B1 | QUINOXALINE INHIBITORS OF THE HEDGEHOG SIGNALLING PATHWAY | GENENTECH INC (US) | 2012-06-20 | — | — | EP | disclosed |