SCHEMBL8351640

SCHEMBL8351640

Nc1nc(NS(=O)(=O)c2cc(Cl)ccc2Cl)n[nH]1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.52
SGK1 O00141 6/20 0.52
HPGD P15428 1/20 0.51
TSHR P16473 1/20 0.51
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
FBP1 P09467 2/20 0.48
GAA P10253 2/20 0.48
MEN1 O00255 1/20 0.48
GFER P55789 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 2/20 0.47
USP2 O75604 1/20 0.47
ESR2 Q92731 1/20 0.47
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10561364 0.99 MCL1 (0.51) MCL1SGK1HPGDTSHRALDH1A1
SCHEMBL10561249 0.83 GAA (0.51) SGK1GAAMEN1GFERKMT2A
SCHEMBL8351204 0.76 KDM1A (0.47) SMN1; SMN2GAAMEN1GFERKMT2A
SCHEMBL356140 0.74 MCL1 (0.58) MCL1HPGDTSHRALDH1A1SMN1; SMN2
SCHEMBL9943352 0.72 GAA (0.45) GAAMEN1GFERKMT2AMAPT
SCHEMBL29118839 0.71 ALDH1A1 (0.67) MCL1SGK1HPGDTSHRALDH1A1
SCHEMBL26662268 0.70 SMN1; SMN2 (0.57) ALDH1A1SMN1; SMN2GAAMEN1GFER
SCHEMBL6259655 0.69 MCL1 (0.66) MCL1HPGDTSHRALDH1A1FBP1
SCHEMBL8356823 0.68 MEN1 (0.51) ALDH1A1SMN1; SMN2GAAMEN1KMT2A
SCHEMBL7996747 0.68 SGK1 (0.61) SGK1ALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565593-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1993-10-20 EP claimed
EP-0562015-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1993-09-29 EP claimed
WO-1992011761-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1992-07-23 WO claimed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO claimed
US-5880066-A COMPOSITION COMPRISING TRIAZOLOPYRIMIDINE SULFONAMIDE HERBICIDE AND OXAZOLIDINE DICHLOROACETAMIDE ANTIDOTE MONSANTO COMPANY (US) 1999-03-09 US disclosed
EP-0565593-B1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO CO (US) 1999-03-03 EP disclosed
EP-0603240-B1 SAFENING HERBICIDAL PYRAZOLYLSULFONYLUREAS MONSANTO CO (US) 1998-12-02 EP disclosed
US-5502025-A ANTIDOTES FOR HERBICIDES AND PLANT SAFTENING AGENTS MONSANTO COMPANY (US) 1996-03-26 US disclosed
US-5484760-A AMIDES MONSANTO COMPANY (US) 1996-01-16 US disclosed
EP-0565593-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1993-10-20 EP disclosed
EP-0562015-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1993-09-29 EP disclosed
EP-0531271-A1 Safening herbicidal pyrazolysulfonylureas MONSANTO COMPANY (US) 1993-03-10 EP disclosed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO disclosed
US-4822404-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1989-04-18 US disclosed
US-4772720-A Process for the preparation of intermediates useful for making herbicidal sulfonamides derived from substituted 2-amino-1,2,4-triazolo(1,5-A)pyrimidines THE DOW CHEMICAL COMPANY (US) 1988-09-20 US disclosed
US-4685958-A Sulfonamides derived from substituted 2-amino-1,2,4-triazolo[1,5-a]-1,3,5-triazines and compositions and methods of controlling undesired vegetation THE DOW CHEMICAL COMPANY (US) 1987-08-11 US disclosed
US-4650892-A ARYLSULFONAMIDE AND DIMETHYL N-CYANODTHIOIMINO CARBONATE THE DOW CHEMICAL COMPANY (US) 1987-03-17 US disclosed
US-4638075-A CHEMICAL INTERMEDIATES FOR TRIAZOLO (1,5A) PYRIMIDINES THE DOW CHEMICAL COMPANY (US) 1987-01-20 US disclosed
EP-0188225-A1 Process for the preparation of herbicidal sulfonamides derived from substituted 2-amino-1,2,4 triazolo (1,5-a) pyrimidines and novel intermediates provided therein THE DOW CHEMICAL COMPANY (US) 1986-07-23 EP disclosed
EP-0150974-A2 Novel sulfonamides derived from substituted 2-amino-1,2,4-triazolo(1,5-a)pyrimidines and compositions and methods of controlling undesired vegetation THE DOW CHEMICAL COMPANY (US) 1985-08-07 EP disclosed