Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 17/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728067 | 0.84 | DHODH (0.79) | DHODH | |
| SCHEMBL9943405 | 0.81 | DHODH (0.61) | DHODHNR4A2 | |
| SCHEMBL3728325 | 0.80 | DHODH (0.67) | DHODH | |
| SCHEMBL729452 | 0.74 | DHODH (1.00) | DHODH | |
| SCHEMBL728088 | 0.72 | DHODH (0.75) | DHODH | |
| SCHEMBL290518 | 0.71 | DHODH (0.81) | DHODH | |
| SCHEMBL3873430 | 0.70 | DHODH (0.82) | DHODH | |
| SCHEMBL729533 | 0.70 | DHODH (1.00) | DHODH | |
| SCHEMBL3872768 | 0.70 | DHODH (0.80) | DHODH | |
| SCHEMBL729482 | 0.69 | DHODH (0.78) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121614-B1 | AMINO NICOTINIC AND ISONICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL SA (ES) | 2012-06-20 | — | — | EP | disclosed |