Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260334 | 0.81 | PTGS1 (0.40) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL918474 | 0.81 | CA1 (0.45) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL20165714 | 0.81 | CA1 (0.45) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL3731600 | 0.79 | KMT2A (0.47) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL10818954 | 0.79 | KMT2A (0.47) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL11053762 | 0.78 | KMT2A (0.39) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL3823777 | 0.76 | CA1 (0.45) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL11904307 | 0.76 | CA1 (0.41) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL2691668 | 0.75 | PTGS1 (0.44) | CA1CA2CA4PTGS1PTGS2 | |
| SCHEMBL4128734 | 0.74 | NOS1 (0.45) | CA1CA2CA4PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464632-A1 | PYRIMIDONE DERIVATIVES USED AS TAU PROTEIN KINASE 1 INHIBITORS | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-06-20 | — | — | EP | disclosed |