Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304697 | 0.81 | GPR119 (0.39) | GPR119 | |
| SCHEMBL9943531 | 0.74 | GPR119 (0.56) | GPR119 | |
| SCHEMBL24687442 | 0.72 | ADORA2A (0.36) | GPR119 | |
| SCHEMBL6434378 | 0.71 | JAK2 (0.54) | — | |
| SCHEMBL28929649 | 0.71 | SRC (0.46) | — | |
| SCHEMBL21138226 | 0.70 | NAE1 (0.38) | GPR119 | |
| SCHEMBL1450232 | 0.70 | HTR2A (0.33) | — | |
| SCHEMBL21138790 | 0.70 | ADORA2A (0.39) | — | |
| SCHEMBL21159459 | 0.69 | GPR119 (0.46) | GPR119 | |
| SCHEMBL21138227 | 0.69 | GPR119 (0.46) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152707-B1 | [6,5]-BICYCLIC GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2012-06-20 | — | — | EP | disclosed |