Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.65 |
| ▸ | KLK7 | P49862 | 1/20 | 0.65 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 4/20 | 0.54 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12585497 | 1.00 | KLK5 (0.65) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL9943561 | 1.00 | KLK5 (0.65) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL10585294 | 0.95 | KLK5 (0.65) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL4370045 | 0.95 | KLK5 (0.65) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL14300984 | 0.94 | KLK5 (0.64) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL14300985 | 0.94 | KLK5 (0.64) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL5870038 | 0.94 | KLK5 (0.64) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL344670 | 0.92 | PPARA (0.63) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL344669 | 0.92 | PPARA (0.63) | KLK5KLK7PPARASYKCTSS | |
| SCHEMBL84710 | 0.92 | PPARA (0.63) | KLK5KLK7PPARASYKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8747809-B2 | Single diastereomers of 4-fluoroglutamine and methods of their preparation and use | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-06-10 | — | — | US | disclosed |
| US-20120288444-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS OF THEIR PREPARATION AND USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2012-11-15 | — | — | US | disclosed |
| EP-2464223-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS FOR THEIR PREPARATION AND USE | The Trustees Of The University Of Pennsylvania (US) | 2012-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120288444-A1 | SINGLE DIASTEREOMERS OF 4-FLUOROGLUTAMINE AND METHODS OF THEIR PREPARATION AND USE | GCG, FPGS, FOLH1 | KLK5 635/4885KLK7 742/4885PPARA 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.