Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CASR | P41180 | 3/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027575 | 0.85 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL11501560 | 0.83 | TDP1 (0.41) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL114856 | 0.77 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL9346593 | 0.77 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL9065284 | 0.77 | TDP1 (0.44) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL9809603 | 0.76 | PTPN1 (0.37) | TDP1CYP1A2CYP2A6ALDH1A1MEN1 | |
| SCHEMBL18242406 | 0.75 | TDP1 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL144686 | 0.75 | TP53 (0.42) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL9249654 | 0.74 | TDP1 (0.34) | TDP1TP53CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL6838457 | 0.74 | CYP2C9 (0.39) | TDP1TP53CYP1A2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464670-A1 | PROCESSES FOR CONTROLLING THE VISCOSITY OF POLYALPHAOLEFINS | Chemtura Corporation (US) | 2012-06-20 | — | — | EP | disclosed |