Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.45 |
| ▸ | GABRD | O14764 | 2/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.45 |
| ▸ | GABRE | P78334 | 2/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.45 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9105431 | 1.00 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Trifluoroacetic Acid SCHEMBL9105443 | 1.00 | GABRP (0.45) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8565157 | 0.88 | — | — | |
| SCHEMBL8565158 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL384861 | 0.86 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL384070 | 0.86 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Trifluoroacetic Acid SCHEMBL9943858 | 0.82 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Trifluoroacetic Acid SCHEMBL9101130 | 0.82 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Trifluoroacetic Acid SCHEMBL9101138 | 0.82 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Trifluoroacetic Acid SCHEMBL9943896 | 0.81 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464368-A1 | CATHEPSIN C INHIBITORS | Glaxo Group Limited (GB) | 2012-06-20 | — | — | EP | disclosed |