Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656502 | 1.00 | KMT2A (0.47) | KMT2AMEN1HSD11B1HDAC1HDAC6 | |
| SCHEMBL8656510 | 1.00 | KMT2A (0.47) | KMT2AMEN1HSD11B1HDAC1HDAC6 | |
| SCHEMBL3225070 | 0.86 | KMT2A (0.50) | KMT2AMEN1L3MBTL1TSHRALDH1A1 | |
| SCHEMBL2327943 | 0.86 | KMT2A (0.46) | KMT2AMEN1HSD11B1HDAC1HDAC6 | |
| SCHEMBL2331058 | 0.83 | KMT2A (0.44) | KMT2AMEN1HSD11B1HDAC1HDAC6 | |
| SCHEMBL12984130 | 0.82 | ALDH1A1 (0.47) | KMT2AMEN1HDAC1HDAC6L3MBTL1 | |
| SCHEMBL10660607 | 0.81 | MEN1 (0.49) | KMT2AMEN1HDAC1HDAC6HDAC3 | |
| SCHEMBL1388218 | 0.80 | EPOR (0.46) | KMT2AMEN1HSD11B1TRPM8CTSK | |
| SCHEMBL27462544 | 0.80 | EPOR (0.46) | KMT2AMEN1HSD11B1TRPM8CTSK | |
| SCHEMBL1004997 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464639-A1 | PYRIMIDONE DERIVATIVES USED AS TAU PROTEIN KINASE 1 INHIBITORS | Mitsubishi Tanabe Pharma Corporation (JP) | 2012-06-20 | — | — | EP | disclosed |