SCHEMBL9944023

SCHEMBL9944023

CCc1cc(C(F)(C(F)(F)F)C(F)(F)F)cc(C)c1NC(=O)c1ccc(-n2cncn2)c(NC(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
CYP1A2 P05177 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
KDM4E B2RXH2 1/20 0.51
GAA P10253 1/20 0.51
GRM7 Q14831 5/20 0.48
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9946453 0.93 GRM7 (0.49) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL17399561 0.92 ALDH1A1 (0.46) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL1275752 0.89 ALDH1A1 (0.44) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL14562859 0.89 ALDH1A1 (0.50) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL9894411 0.89 ALDH1A1 (0.43) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL299819 0.89 ALDH1A1 (0.55) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL1275123 0.89 ALDH1A1 (0.44) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL13076340 0.88 ALDH1A1 (0.49) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL1275839 0.87 ALDH1A1 (0.45) ALDH1A1MAPTHPGDCYP1A2CYP2C9
SCHEMBL1275829 0.87 ALDH1A1 (0.43) ALDH1A1MAPTHPGDCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3153497-A2 PESTICIDAL CARBOXAMIDES Bayer Cropscience AG (DE) 2017-04-12 EP disclosed
EP-2464624-A2 PESTICIDAL CARBOXAMIDES Bayer CropScience AG (DE) 2012-06-20 EP disclosed