Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244283 | 0.85 | MAPT (0.83) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL701512 | 0.84 | TSHR (0.68) | POLBLMNATAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL9944160 | 0.84 | MEN1 (0.56) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL1457750 | 0.82 | GAA (0.71) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL12825328 | 0.82 | GAA (0.56) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL1458179 | 0.82 | MEN1 (0.57) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL1457774 | 0.81 | MEN1 (0.62) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL9944075 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL9944137 | 0.80 | MAPT (0.60) | MEN1KMT2AMAPTPOLBLMNA | |
| SCHEMBL14291460 | 0.79 | KMT2A (0.69) | MEN1KMT2AMAPTLMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447028-B2 | Therapeutic aryl-amido-aryl compounds and their use | KING'S COLLEGE LONDON (GB) | 2016-09-20 | — | — | US | disclosed |
| US-20160039747-A1 | Therapeutic Aryl-Amido-Aryl Compounds and Their Use | KING'S COLLEGE LONDON (GB) | 2016-02-11 | — | — | US | disclosed |
| US-20120149737-A1 | Therapeutic Aryl-Amido-Aryl Compounds and Their Use | KING'S COLLEGE LONDON (GB) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149737-A1 | Therapeutic Aryl-Amido-Aryl Compounds and Their Use | RARA, RARB, RARG | MEN1 4809/4885KMT2A 1418/4885MAPT 150/4885 |
| US-20160039747-A1 | Therapeutic Aryl-Amido-Aryl Compounds and Their Use | RARA, RARB, RARG | MEN1 4809/4885KMT2A 1418/4885MAPT 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.