SCHEMBL994414

SCHEMBL994414

CN1C(C)(C)CC(OC(=O)CCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)CC1(C)C

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
GAA P10253 7/20 0.46
MAOB P27338 3/20 0.41
MAOA P21397 2/20 0.41
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 3/20 0.39
MAPT P10636 1/20 0.39
ACHE P22303 1/20 0.39
PKM P14618 1/20 0.38
HTT P42858 1/20 0.38
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
THRB P10828 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL562628 0.91 KMT2A (0.47) KMT2AMEN1GAAMAOBMAOA
SCHEMBL11449728 0.90 KMT2A (0.45) KMT2AMEN1GAAMAOBMAOA
SCHEMBL8880154 0.88 KMT2A (0.46) KMT2AMEN1GAAMAOBMAOA
SCHEMBL14399902 0.88 ALDH1A1 (0.41) KMT2AMEN1GAAALDH1A1KDM4E
SCHEMBL14949946 0.88 KMT2A (0.43) KMT2AMEN1GAAMAOBMAOA
SCHEMBL10575745 0.87 KMT2A (0.45) KMT2AMEN1GAAMAOBMAOA
SCHEMBL206978 0.87 KMT2A (0.43) KMT2AMEN1GAAMAOBMAOA
SCHEMBL11449677 0.86 KMT2A (0.44) KMT2AMEN1GAAMAOBMAOA
SCHEMBL11449678 0.86 KMT2A (0.44) KMT2AMEN1GAAMAOBMAOA
SCHEMBL4824520 0.86 MAOB (0.40) KMT2AMEN1GAAMAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365380-B1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-04-26 EP disclosed
US-11542389-B2 Vinyl chloride polymers and compositions for additive manufacturing AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-01-03 US disclosed
US-20210017374-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2021-01-21 US disclosed
US-10365411-B2 Hardcoat film, polarizing plate, liquid crystal display, and method for manufacturing hardcoat film FUJIFILM CORPORATION (JP) 2019-07-30 US disclosed
US-9951205-B2 Stable compositions of thiabendazole and iodine-containing fungicides LANXESS DEUTSCHLAND GMBH (DE) 2018-04-24 US disclosed
US-20170322345-A1 HARDCOAT FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD FOR MANUFACTURING HARDCOAT FILM FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
EP-2413697-B1 STABILISATION OF COMPOUNDS CONTAINING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2017-11-08 EP disclosed
US-9585384-B2 Stabilization of compounds comprising iodine LANXESS DEUTSCHLAND GMBH (DE) 2017-03-07 US disclosed
CN-103857737-B Use the mannich compound based on amino-triazine to carry out stability of organic materials BOREALIS AG (AT) 2016-05-25 CN disclosed
US-20160124123-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY USING THE SAME FUJIFILM CORPORATION (JP) 2016-05-05 US disclosed
EP-0016723-B1 LIGHT STABILISATION OF TWO-LAYER COMPOSITE LACQUERS CIBA-GEIGY AG (CH) 1983-06-01 EP disclosed
EP-0015230-B1 STABILIZED ORGANIC POLYMER COMPRISING 2-(2-HYDROXY-3,5-DI-TERT-OCTYLPHENYL)-2H-BENZOTRIAZOLE AS A LIGHT-STABILIZER CIBA-GEIGY AG (CH) 1983-02-23 EP disclosed
US-4340533-A 2,2,6,6-TETRAMETHYL PIPERIDINE ACYLATED DERIVATIVES PROVIDE RESISTANCE TO HEAT AND LIGHT CIBA-GEIGY CORPORATION (US) 1982-07-20 US disclosed
EP-0013443-B1 2,2,6,6-TETRAMETHYLPIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND SYNTHETIC POLYMERS STABILIZED WITH THE AID THEREOF CIBA-GEIGY AG (CH) 1982-03-31 EP disclosed
US-4315848-A PROTECTIVE COATING FOR AUTOMOBILES CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4314933-A 2,2,6,6-TETRAALKYLPIPERIDINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1982-02-09 US disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4237294-A STABILIZERS FOR POLYMERS SANKYO COMPANY, LIMITED (JP) 1980-12-02 US disclosed
EP-0013443-A1 2,2,6,6-Tetramethylpiperidine derivatives, process for their preparation and synthetic polymers stabilized with the aid thereof CIBA-GEIGY AG (CH) 1980-07-23 EP disclosed