SCHEMBL994418

SCHEMBL994418

CCCCCOc1ccc2cccc(OCCCCC)c2n1

nearest known ligand 0.73

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 8/20 0.73
NCF1 P14598 4/20 0.51
KDM4E B2RXH2 3/20 0.46
LMNA P02545 3/20 0.46
MAPT P10636 2/20 0.46
TLR8 Q9NR97 2/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GAA P10253 1/20 0.46
HTR1B P28222 1/20 0.46
HTT P42858 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10063304 0.95 MCHR1 (0.72) MCHR1NCF1KDM4ELMNAMAPT
SCHEMBL20696659 0.86 MCHR1 (0.56) MCHR1LMNAMAPTMEN1NPC1
SCHEMBL13904506 0.86 MCHR1 (0.68) MCHR1NCF1KDM4ELMNAMAPT
SCHEMBL20696658 0.84 MCHR1 (0.54) MCHR1NCF1KDM4ETLR8MEN1
SCHEMBL5883752 0.84 MCHR1 (1.00) MCHR1NCF1
SCHEMBL28065654 0.84 MCHR1 (0.72) MCHR1NCF1KDM4ELMNAMAPT
SCHEMBL10682868 0.84 MCHR1 (0.72) MCHR1NCF1KDM4ELMNAMAPT
SCHEMBL5884086 0.83 MCHR1 (1.00) MCHR1NCF1
SCHEMBL7259257 0.83 MCHR1 (1.00) MCHR1NCF1
SCHEMBL9568616 0.82 MAPT (0.66) MCHR1KDM4ELMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2456793-A1 CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS Equistar Chemicals, LP (US) 2012-05-30 EP claimed
EP-2456795-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS Equistar Chemicals, LP (US) 2012-05-30 EP claimed
US-8158733-B2 Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands EQUISTAR CHEMICALS, LP (US) 2012-04-17 US claimed
WO-2011011039-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO claimed
US-20110021344-A1 Method for preparing non-metallocene ligands EQUISTAR CHEMICALS, LP 2011-01-27 US claimed
US-20110021727-A1 Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands EQUISTAR CHEMICALS, LP 2011-01-27 US claimed
WO-2011011040-A1 CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO claimed
EP-3478694-B9 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-08-04 EP disclosed
EP-3478694-B1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-12-09 EP disclosed
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-10-27 US disclosed
US-10562987-B2 Polymers produced via use of quinolinyldiamido transition metal complexes and vinyl transfer agents EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-02-18 US disclosed
US-20190177449-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2019-06-13 US disclosed
EP-3478694-A1 QUINOLINYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF ExxonMobil Chemical Patents Inc. (US) 2019-05-08 EP disclosed
EP-2456795-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS Equistar Chemicals, LP (US) 2012-05-30 EP disclosed
US-8158733-B2 Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands EQUISTAR CHEMICALS, LP (US) 2012-04-17 US disclosed
US-8153544-B2 Method for preparing non-metallocene catalysts EQUISTAR CHEMICALS, LP (US) 2012-04-10 US disclosed
WO-2011011039-A1 METHOD OF PREPARING NON-METALLOCENE CATALYSTS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO disclosed
US-20110021344-A1 Method for preparing non-metallocene ligands EQUISTAR CHEMICALS, LP 2011-01-27 US disclosed
US-20110021727-A1 Catalysts based on 2-(2-aryloxy)quinoline or 2-(2-aryloxy)dihydroquinoline ligands EQUISTAR CHEMICALS, LP 2011-01-27 US disclosed
WO-2011011040-A1 CATALYSTS BASED ON 2-(2-ARYLOXY) QUINOLINE OR 2-(2-ARYLOXY) DIHYDROQUNIOLINE LIGANDS EQUISTAR CHEMICALS, LP (US) 2011-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815318-B2 Quinolinyldiamido transition metal complexes, production and use thereof PARN, PARG, PICALM MCHR1 4740/4885NCF1 1493/4885KDM4E 4392/4885
US-20190177449-A1 Quinolinyldiamido Transition Metal Complexes, Production and Use Thereof PARN, PARG, PICALM MCHR1 4740/4885NCF1 1493/4885KDM4E 4392/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.