Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865983 | 0.83 | ALDH1A1 (0.45) | SMN1; SMN2KDM4EALDH1A1SYKAURKB | |
| SCHEMBL9945448 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EALDH1A1SYKAURKB | |
| SCHEMBL20732817 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2KDM4EALDH1A1SYKCYP1A2 | |
| SCHEMBL13754806 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2KDM4EALDH1A1CYP1A2HRH3 | |
| SCHEMBL9944264 | 0.74 | SYK (0.46) | SMN1; SMN2KDM4EALDH1A1SYKAURKB | |
| SCHEMBL9944318 | 0.74 | NPC1 (0.42) | SMN1; SMN2KDM4EALDH1A1SYKCYP1A2 | |
| SCHEMBL14075065 | 0.73 | SMN1; SMN2 (0.45) | SMN1; SMN2KDM4EALDH1A1SYKCYP1A2 | |
| SCHEMBL17217699 | 0.73 | NPC1 (0.47) | SMN1; SMN2ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL8472048 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EALDH1A1SYKHRH1 | |
| SCHEMBL9944275 | 0.73 | NPC1 (0.47) | SMN1; SMN2ALDH1A1NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772290-B2 | Alpha-arylmethoxyacrylate derivative, preparation method thereof, and pharmaceutical composition containing same | Oscotech Inc. (KR) | 2014-07-08 | — | — | US | disclosed |
| US-20120149707-A1 | ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | OSCOTEC INC. (KR) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149707-A1 | ALPHA-ARYLMETHOXYACRYLATE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | HIF1A, HIF1AN, EGLN3 | SMN1; SMN2 3764/4885KDM4E 533/4885ALDH1A1 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.