SCHEMBL9945415

SCHEMBL9945415

CC(C)(COP(=O)(O)OP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1OP(=O)(O)O)C(O)C(=O)NCCC(=O)NCCC(=O)CCCO

nearest known ligand 0.88

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ EP300 Q09472 3/20 0.88
▸ CHAT P28329 2/20 0.88
▸ NAA50 Q9GZZ1 2/20 0.88
▸ AURKA O14965 2/20 0.88
▸ KAT5 Q92993 2/20 0.88
▸ KAT2B Q92831 1/20 0.88
▸ CREBBP Q92793 1/20 0.71
▸ NAA40 Q86UY6 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16216007 0.95 EP300 (0.89) EP300CHATNAA50AURKAKAT5
Coenzyme_A SCHEMBL28724953 0.94 EP300 (0.90) EP300CHATNAA50AURKAKAT5
Coenzyme_A SCHEMBL2119660 0.94 EP300 (0.90) EP300CHATNAA50AURKAKAT5
SCHEMBL14124928 0.94 EP300 (0.86) EP300CHATNAA50AURKAKAT5
SCHEMBL18925866 0.94 NAA50 (0.84) EP300CHATNAA50AURKAKAT5
SCHEMBL21314167 0.94 NAA50 (0.84) EP300CHATNAA50AURKAKAT5
SCHEMBL29806102 0.94 NAA50 (0.84) EP300CHATNAA50AURKAKAT5
SCHEMBL14918771 0.94 NAA50 (0.84) EP300CHATNAA50AURKAKAT5
SCHEMBL14124932 0.94 EP300 (0.85) EP300CHATNAA50AURKAKAT5
SCHEMBL14124919 0.94 EP300 (0.86) EP300CHATNAA50AURKAKAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9968431-B2 Coatings for the manufacture and application of polyhydroxyalkanoate medical devices TEPHA, INC. (US) 2018-05-15 — — US disclosed
US-9943393-B2 Coatings for the manufacture and application of polyhydroxyalkanoate medical devices TEPHA, INC. (US) 2018-04-17 — — US disclosed
US-9326841-B2 Coatings for the manufacture and application of polyhydroxyalkanoate medical devices TEPHA, INC. (US) 2016-05-03 — — US disclosed
US-9162010-B2 Drug eluting cochlear implants TEPHA, INC. (US) 2015-10-20 — — US disclosed
US-20140363672-A1 Coatings for the Manufacture and Application of Polyhydroxyalkanoate Medical Devices TEPHA, INC. (US) 2014-12-11 — — US disclosed
US-20140248417-A1 Coatings for the Manufacture and Application of Polyhydroxyalkanoate Medical Devices TEPHA, INC. (US) 2014-09-04 — — US disclosed
US-8753555-B2 Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers TEPHA, INC. (US) 2014-06-17 — — US disclosed
US-8747468-B2 Coatings for the manufacture and application of polyhydroxyalkanoate medical devices TEPHA, INC. (US) 2014-06-10 — — US disclosed
US-20140046351-A1 Coatings for the Manufacture and Application of Polyhydroxyalkanoate Medical Devices TEPHA, INC. (US) 2014-02-13 — — US disclosed
US-20120283666-A1 DRUG ELUTING COCHLEAR IMPLANTS TEPHA, INC. 2012-11-08 — — US disclosed
US-20120150285-A1 MEDICAL DEVICES CONTAINING DRY SPUN NON-WOVENS OF POLY-4-HYDROXYBUTYRATE AND COPOLYMERS TEPHA, INC. 2012-06-14 — — US disclosed
US-20120053689-A1 COATINGS FOR THE MANUFACTURE AND APPLICATION OF POLYHYDROXYALKANOATE MEDICAL DEVICES TEPHA, INC. 2012-03-01 — — US disclosed
US-20110189475-A1 MEDICAL DEVICES CONTAINING ORIENTED FILMS OF POLY-4-HYDROXYBUTYRATE AND COPOLYMERS TEPHA, INC. 2011-08-04 — — US disclosed
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