Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14988690 | 0.78 | SRC (0.45) | SRCERN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL9945945 | 0.77 | KMT2A (0.36) | LMNAALDH1A1GAAKDM4E | |
| SCHEMBL12538919 | 0.77 | SRC (0.47) | SRCERN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL1252425 | 0.75 | CA1 (0.42) | SRCLMNAALDH1A1GAASMN1; SMN2 | |
| SCHEMBL310863 | 0.72 | ERN1 (0.67) | SRCERN1LMNAALDH1A1GAA | |
| SCHEMBL7284734 | 0.71 | SRC (0.52) | SRCERN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL20831956 | 0.70 | ERN1 (0.51) | SRCERN1LMNAALDH1A1CYP1A2 | |
| SCHEMBL7290764 | 0.70 | SRC (0.47) | SRCERN1LMNAALDH1A1GAA | |
| SCHEMBL18319253 | 0.70 | LMNA (0.51) | LMNAALDH1A1GAAKDM4ENPSR1 | |
| SCHEMBL14036616 | 0.70 | LMNA (0.47) | ERN1LMNAALDH1A1CYP1A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | SRC 1082/4885ERN1 2855/4885LMNA 3453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.