Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306551 | 0.83 | ALDH1A1 (0.64) | ALDH1A1SRD5A2RAB9AHPGDNPC1 | |
| SCHEMBL16426156 | 0.80 | TSHR (0.57) | ALDH1A1SRD5A2HPGDSMN1; SMN2CES2 | |
| Benzophenone SCHEMBL31103599 | 0.79 | ALDH1A1 (0.82) | ALDH1A1SRD5A2RAB9AHPGDNPC1 | |
| SCHEMBL314267 | 0.79 | ALDH1A1 (0.93) | ALDH1A1SRD5A2RAB9AHPGDNPC1 | |
| SCHEMBL9066312 | 0.79 | ALDH1A1 (0.93) | ALDH1A1SRD5A2RAB9AHPGDNPC1 | |
| SCHEMBL257614 | 0.78 | CA1 (0.65) | ALDH1A1SRD5A2RAB9ANPC1L3MBTL1 | |
| Phenyl Methyl Borinic Acid SCHEMBL120622 | 0.77 | — | — | |
| Benzophenone SCHEMBL7454682 | 0.77 | ALDH1A1 (0.88) | ALDH1A1SRD5A2RAB9AHPGDNPC1 | |
| Benzophenone SCHEMBL30537001 | 0.76 | ALDH1A1 (1.00) | ALDH1A1SRD5A2RAB9AHPGDNPC1 | |
| Benzophenone SCHEMBL28491203 | 0.76 | ALDH1A1 (1.00) | ALDH1A1SRD5A2RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885SRD5A2 3009/4885RAB9A 1191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.