Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.64 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | HPD | P32754 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946047 | 0.87 | MAOB (0.62) | MAOBMAOA | |
| SCHEMBL9946080 | 0.86 | MAOB (0.65) | MAOBMAOANR1H4 | |
| SCHEMBL29952469 | 0.86 | MAOB (0.62) | MAOBMAOANPC1RAB9AAPP | |
| SCHEMBL12182456 | 0.81 | MAOB (0.74) | MAOBMAOANPC1RAB9AAPP | |
| SCHEMBL9946078 | 0.80 | MAOB (0.56) | MAOBMAOANPC1RAB9AAPP | |
| SCHEMBL9946043 | 0.78 | MAOB (0.66) | MAOBMAOA | |
| SCHEMBL11300058 | 0.78 | MAOB (0.70) | MAOBMAOANPC1RAB9AAPP | |
| SCHEMBL1549250 | 0.77 | MAOB (0.68) | MAOBMAOAAPP | |
| SCHEMBL4639670 | 0.77 | MAOB (0.72) | MAOBMAOANPC1RAB9AAPP | |
| SCHEMBL8033064 | 0.77 | MAOB (0.68) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | MAOB 780/4885MAOA 809/4885NPC1 1529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.