Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.53 |
| ▸ | HPD | P32754 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12420271 | 0.89 | ENPP2 (0.54) | MAOBENPP2APPF2 | |
| SCHEMBL22563 | 0.88 | ENPP2 (0.67) | MAOBENPP2APPNPC1RAB9A | |
| SCHEMBL2561649 | 0.88 | ENPP2 (0.53) | MAOBMAOAENPP2F2 | |
| SCHEMBL17236537 | 0.87 | APP (0.53) | MAOBENPP2APPRAB9AF2 | |
| SCHEMBL29951430 | 0.86 | MAOB (0.63) | MAOBMAOAENPP2NR1H4 | |
| SCHEMBL16687440 | 0.86 | ENPP2 (0.56) | MAOBENPP2APPF2 | |
| SCHEMBL9946045 | 0.86 | MAOB (0.64) | MAOBMAOAHPDNR1H4APP | |
| SCHEMBL22315 | 0.85 | CYP4F2 (0.58) | MAOBMAOAENPP2RAB9A | |
| SCHEMBL2560315 | 0.85 | ENPP2 (0.54) | MAOBENPP2APPNPC1RAB9A | |
| SCHEMBL23988 | 0.84 | NR4A2 (0.58) | MAOBMAOAENPP2HPDAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |