Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966292 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL12333623 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL13721260 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL6123843 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL17087772 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL302043 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL36869 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL2389596 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL13720763 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E | |
| SCHEMBL12386343 | 0.79 | ALDH1A1 (0.72) | ALDH1A1MAPTL3MBTL1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149693-A1 | THERAPEUTIC COMPOUNDS | HTR2C, GRK2, GRK3 | ALDH1A1 4010/4885MAPT 2718/4885L3MBTL1 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.