Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6596976 | 0.91 | ALOX15 (0.57) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL11071934 | 0.71 | ALOX15 (0.30) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL131103 | 0.70 | ALOX15 (0.69) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL131104 | 0.70 | ALOX15 (0.69) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL11065471 | 0.69 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL18431213 | 0.69 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL6596970 | 0.69 | ALOX15 (0.58) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL11074810 | 0.69 | ALOX15 (0.58) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL814266 | 0.69 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 | |
| SCHEMBL19696489 | 0.67 | ALOX15 (0.72) | ALOX15ALDH1A1LMNAMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012078667-A2 | COMPOSITIONS AND METHODS RELATING TO PROLIFERATIVE DISEASES | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-06-14 | — | — | WO | disclosed |