Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9947040 | 0.82 | PTGES (0.73) | PTGES | |
| SCHEMBL9947038 | 0.77 | PTGES (0.80) | PTGES | |
| SCHEMBL9947036 | 0.76 | PTGES (0.79) | PTGES | |
| SCHEMBL9947041 | 0.75 | PTGES (0.80) | PTGES | |
| SCHEMBL9898453 | 0.74 | PTGES (0.68) | PTGES | |
| SCHEMBL9947039 | 0.74 | PTGES (0.80) | PTGES | |
| SCHEMBL9897172 | 0.73 | PTGES (0.83) | PTGES | |
| SCHEMBL9898964 | 0.73 | PTGES (0.64) | PTGES | |
| SCHEMBL9946606 | 0.72 | PTGES (1.00) | PTGES | |
| SCHEMBL9946666 | 0.72 | PTGES (1.00) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076673-A1 | 6-AMINO-2-PHENYLAMINO-1H-BENZIMIDAZOLE-5-CARBOXAMIDE- DERIVATIVES AND THEIR USE AS MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |