SCHEMBL9949539

SCHEMBL9949539

CC(C)(C)c1ccc(OP(=O)(O)Cl)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
TRPV1 Q8NER1 1/20 0.43
LMNA P02545 3/20 0.41
POLB P06746 2/20 0.41
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HPGD P15428 1/20 0.41
HDAC1 Q13547 1/20 0.41
ALOX15 P16050 1/20 0.41
APEX1 P27695 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11790553 0.84 CA1 (0.46) MAPTTDP1L3MBTL1SMN1; SMN2CA1
SCHEMBL284462 0.84 SRC (0.54) MAPTTDP1L3MBTL1SMN1; SMN2CA1
SCHEMBL6337668 0.84 CA1 (0.46) MAPTTDP1L3MBTL1SMN1; SMN2CA1
SCHEMBL504554 0.84 MAPT (0.49) MAPTTDP1L3MBTL1SMN1; SMN2CA1
SCHEMBL9485955 0.83 SRC (0.48) SMN1; SMN2CA1CA2CA9CYP2C19
SCHEMBL2149800 0.82 MAPT (0.47) MAPTTDP1L3MBTL1SMN1; SMN2CA1
SCHEMBL2339030 0.82 MAPT (0.47) MAPTTDP1L3MBTL1SMN1; SMN2CA1
SCHEMBL6545239 0.82 SRC (0.52) MAPTTDP1L3MBTL1SMN1; SMN2CA1
SCHEMBL6545019 0.82 SRC (0.52) MAPTTDP1L3MBTL1SMN1; SMN2CA1
Lithium SCHEMBL30523260 0.82 MAPT (0.47) MAPTTDP1L3MBTL1SMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410203-B2 Phosphorus compound, method of preparing the same and flame retardant thermoplastic resin composition including the same CHEIL INDUSTRIES INC. (KR) 2013-04-02 US disclosed
US-20120165444-A1 Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2012-06-28 US disclosed
EP-2468814-A1 Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same Cheil Industries Inc. (KR) 2012-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165444-A1 Novel Phosphorus Compound, Method of Preparing the Same and Flame Retardant Thermoplastic Resin Composition Including the Same RPP30, RER1, TAF11 MAPT 2318/4885TDP1 1726/4885L3MBTL1 3571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.