Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000297 | 0.93 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1802889 | 0.92 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1802805 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1803281 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1802538 | 0.83 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL28209291 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1802655 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1800378 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL4319820 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL1805665 | 0.77 | MAPT (0.50) | ALDH1A1MAPTHPGDMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933246-B2 | Process for preparing 1-phenylpyrazoles | BASF SE (DE) | 2015-01-13 | — | — | US | disclosed |
| EP-2473485-B1 | PROCESS FOR PREPARING 1-PHENYLPYRAZOLES | BASF SE (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-8492558-B2 | Method for producing 2-aminobiphenylene | BASF SE (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20130131352-A1 | Process for Preparing 1-phenylpyrazoles | BASF SE (DE) | 2013-05-23 | — | — | US | disclosed |
| US-8362271-B2 | Process for preparing 1-phenylpyrazoles | BASF SE (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20120165544-A1 | Process for Preparing 1-Phenylpyrazoles | BASF SE (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20110301356-A1 | Method for Producing 2-aminobiphenylene | BASF SE (DE) | 2011-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301356-A1 | Method for Producing 2-aminobiphenylene | C5, CBR3, C1S | ALDH1A1 1545/4885MAPT 4066/4885HPGD 2006/4885 |
| US-20130131352-A1 | Process for Preparing 1-phenylpyrazoles | CBR1, CBR3, CYP1A1 | ALDH1A1 431/4885MAPT 4574/4885HPGD 1183/4885 |
| US-20120165544-A1 | Process for Preparing 1-Phenylpyrazoles | AP3B1, AP3M1, AP3D1 | ALDH1A1 333/4885MAPT 4636/4885HPGD 1758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.