SCHEMBL9951189

SCHEMBL9951189

[CH2]CCC(Br)CCCCCCCCC

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.43
PPARD Q03181 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.43
ZDHHC2 Q9UIJ5 1/20 0.43
ZDHHC7 Q9NXF8 1/20 0.39
LMNA P02545 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
FAAH O00519 1/20 0.38
OPRM1 P35372 1/20 0.37
SLC22A1 O15245 1/20 0.36
FDPS P14324 3/20 0.35
GPR84 Q9NQS5 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7647649 1.00 LCK (0.43) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL611888 1.00 LCK (0.43) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL9584564 1.00 LCK (0.43) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL28355783 0.91 LCK (0.43) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL9584643 0.91 LCK (0.43) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL9063811 0.90
SCHEMBL340114 0.87 LCK (0.52) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL5902659 0.87 LCK (0.52) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL3095599 0.87 LCK (0.52) LCKPPARDZDHHC20ZDHHC2ZDHHC7
SCHEMBL12214087 0.87 LCK (0.52) LCKPPARDZDHHC20ZDHHC2ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2468533-B1 Pneumatic tire with composite innerliner GOODYEAR TIRE & RUBBER (US) 2013-12-04 EP disclosed
US-20120160388-A1 PNEUMATIC TIRE WITH COMPOSITE INNERLINER THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-06-28 US disclosed
EP-2468533-A1 Pneumatic tire with composite innerliner The Goodyear Tire & Rubber Company (US) 2012-06-27 EP disclosed