Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | TK2 | O00142 | 1/20 | 0.67 |
| ▸ | PYGM | P11217 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Idoxuridine SCHEMBL51859 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL5983279 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL5983277 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL6519051 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL37714 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL13252710 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL2918701 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL4426782 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL21585076 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| Idoxuridine SCHEMBL10015658 | 1.00 | TK1 (1.00) | TK1LMNASMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654779-A1 | LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF | Ludwig Institute for Cancer Research, Ltd. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012088414-A1 | LIPOSOMAL FORMULATION OF NONGLYCOSIDIC CERAMIDES AND USES THEREOF | LUDWIG INSTITUTE FOR CANCER RESEARCH LTD. (US) | 2012-06-28 | — | — | WO | disclosed |