SCHEMBL995168

SCHEMBL995168

C1=CCC(c2ccccn2)C=C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
MAPT P10636 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
KMT2A Q03164 1/20 0.38
KDM4E B2RXH2 5/20 0.37
LMNA P02545 3/20 0.37
CCR1 P32246 2/20 0.37
CCR5 P51681 2/20 0.37
CCR8 P51685 2/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
METAP1 P53582 1/20 0.37
BLM P54132 1/20 0.37
HIF1A Q16665 1/20 0.37
DOHH Q9BU89 1/20 0.37
P4HTM Q9NXG6 1/20 0.37
DDB1 Q16531 1/20 0.35
CRBN Q96SW2 1/20 0.35
GSK3B P49841 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13168578 0.79
SCHEMBL30659967 0.76
SCHEMBL4076898 0.76
SCHEMBL30059241 0.74 CCR1 (0.42) ALDH1A1KMT2AKDM4ECCR1CCR5
SCHEMBL12958751 0.73 MEN1 (0.52) ALDH1A1MAPTRAB9AKMT2APOLB
SCHEMBL21003780 0.73 MEN1 (0.52) ALDH1A1MAPTRAB9AKMT2APOLB
SCHEMBL26499214 0.72 HTR1A (0.39) KDM4ELMNACCR1CCR5CCR8
SCHEMBL27262119 0.72 DDB1 (0.39) ALDH1A1MAPTNPC1RAB9AKMT2A
SCHEMBL18790246 0.71 CCR1 (0.41) MAPTRAB9ACCR1CCR5CCR8
SCHEMBL8261704 0.71 CCR1 (0.41) ALDH1A1KMT2AKDM4ECCR1CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433167-A Benzo-heterocyclic compound with Snail inhibitory activity, preparation method, pharmaceutical composition and medical application thereof 中国药科大学 2022-12-06 CN claimed
WO-2024249996-A1 HALOGEN-FREE FLAME RETARDANT (METH)ACRYLATE RESINS HENKEL AG & CO. KGAA (DE) 2024-12-05 WO disclosed
US-20230265315-A1 TWO-PART, SILANE MODIFIED POLYMER/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel AG & Holding GmbH (DE) 2023-08-24 US disclosed
EP-4176017-A1 TWO-PART, SILANE MODIFIED POLYMER/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel AG & Co. KGaA (DE) 2023-05-10 EP disclosed
CN-115052860-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-09-13 CN disclosed
US-11254846-B2 Two part adhesive composition LG CHEM, LTD. 2022-02-22 US disclosed
CN-114072385-A Compositions and methods for treating cancer 儿童医院医学中心 2022-02-18 CN disclosed
WO-2022006486-A1 TWO-PART, SILANE MODIFIED POLYMER/FREE RADICALLY CURABLE ADHESIVE SYSTEMS Henkel IP & Holding GmbH (DE) 2022-01-06 WO disclosed
EP-3551623-B1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2021-09-22 EP disclosed
EP-3508541-B1 TWO-COMPONENT ADHESIVE COMPOSITION LG CHEMICAL LTD (KR) 2021-07-14 EP disclosed
WO-2013019326-A9 ELECTRICALLY CONDUCTIVE STRUCTURAL ADHESIVE Henkel US IP LLC (US) 2014-06-12 WO disclosed
EP-2739690-A2 ELECTRICALLY CONDUCTIVE STRUCTURAL ADHESIVE Henkel US IP LLC (US) 2014-06-11 EP disclosed
WO-2013019326-A2 ELECTRICALLY CONDUCTIVE STRUCTURAL ADHESIVE HENKEL CORPORATION (US) 2013-02-07 WO disclosed
US-8231758-B2 Acrylic adhesives HENKEL CORPORATION (US) 2012-07-31 US disclosed
EP-2449047-A2 ULTRAFAST HEAT/ROOM TEMPERATURE ADHESIVE COMPOSITION FOR BONDING APPLICATIONS Henkel Corporation (US) 2012-05-09 EP disclosed
WO-2011002876-A2 ULTRAFAST HEAT/ROOM TEMPERATURE ADHESIVE COMPOSITION FOR BONDING APPLICATIONS HENKEL CORPORATION (US) 2011-01-06 WO disclosed
US-20100331462-A1 ULTRAFAST HEAT/ROOM TEMPERATURE ADHESIVE COMPOSITION FOR BONDING APPLICATIONS HENKEL CORPORATION (US) 2010-12-30 US disclosed
US-20100101724-A1 ACRYLIC ADHESIVES HENKEL CORPORATION (US) 2010-04-29 US disclosed
WO-2009009009-A2 ACRYLIC ADHESIVES HENKEL CORPORATION (US) 2009-01-15 WO disclosed
WO-2007078185-A1 METALLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2007-07-12 WO disclosed