Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9951844 | 0.89 | REN (0.52) | RENKCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9952555 | 0.87 | REN (0.59) | RENKCNH2CYP3A4 | |
| SCHEMBL696532 | 0.87 | REN (0.56) | RENKCNH2CYP3A4 | |
| SCHEMBL9951650 | 0.86 | REN (0.64) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL9952796 | 0.86 | REN (0.63) | RENCYP3A4 | |
| SCHEMBL694511 | 0.83 | REN (0.58) | RENKCNH2CYP3A4 | |
| SCHEMBL9959099 | 0.83 | REN (0.51) | RENCYP3A4 | |
| Hydrochloric Acid SCHEMBL9959265 | 0.82 | REN (0.51) | RENCYP3A4 | |
| SCHEMBL696074 | 0.82 | REN (0.63) | RENKCNH2CYP3A4 | |
| Hydrochloric Acid SCHEMBL9952695 | 0.81 | REN (0.55) | RENKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085935-A2 | COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2012-06-28 | — | — | WO | claimed |
| WO-2012085935-A2 | COMPOUNDS AS INHIBITORS OF RENIN | CADILA HEALTHCARE LIMITED (IN) | 2012-06-28 | — | — | WO | disclosed |