Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995204 | 1.00 | MEN1 (0.59) | MEN1KMT2AATMPOLBRAB9A | |
| Hydrochloric Acid SCHEMBL10275815 | 0.99 | MEN1 (0.57) | MEN1KMT2AATMPOLBRAB9A | |
| Hydrochloric Acid SCHEMBL10275819 | 0.99 | MEN1 (0.57) | MEN1KMT2AATMPOLBRAB9A | |
| SCHEMBL995024 | 0.87 | ATM (0.58) | MEN1KMT2AATM | |
| SCHEMBL995027 | 0.87 | ATM (0.58) | MEN1KMT2AATM | |
| SCHEMBL995763 | 0.86 | LMNA (0.54) | MEN1KMT2AATMPOLBFAAH | |
| SCHEMBL995762 | 0.86 | LMNA (0.54) | MEN1KMT2AATMPOLBFAAH | |
| Hydrochloric Acid SCHEMBL10276210 | 0.86 | ATM (0.57) | MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL10276205 | 0.86 | ATM (0.57) | MEN1KMT2AATM | |
| SCHEMBL995515 | 0.85 | KDM4E (0.54) | MEN1KMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2801568-A1 | Benzene-sulphonamide compounds, method for synthesising and use in medicine and in cosmetics | Galderma Research & Development (FR) | 2014-11-12 | — | — | EP | disclosed |
| EP-2448920-B1 | Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine | GALDERMA RES & DEV (FR) | 2014-08-13 | — | — | EP | disclosed |
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |