Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 9/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.35 |
| ▸ | MERTK | Q12866 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9953549 | 0.93 | PIK3CD (0.35) | PIK3CDAXLMERTK | |
| SCHEMBL9953147 | 0.90 | PIK3CD (0.37) | PIK3CDAXLMERTK | |
| Trifluoroacetic Acid SCHEMBL9952183 | 0.86 | PIK3CD (0.37) | PIK3CDAXLMERTK | |
| SCHEMBL9929351 | 0.83 | PIK3CD (0.44) | PIK3CDAXLMERTK | |
| SCHEMBL9960484 | 0.82 | PIK3CD (0.35) | PIK3CDALDH1A1 | |
| SCHEMBL17147215 | 0.79 | PIK3CD (0.47) | PIK3CDAXLMERTK | |
| Trifluoroacetic Acid SCHEMBL9929573 | 0.78 | PIK3CD (0.41) | PIK3CDAXLMERTK | |
| SCHEMBL9952900 | 0.78 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL9952126 | 0.77 | PDE5A (0.33) | — | |
| SCHEMBL9929054 | 0.76 | PIK3CD (0.43) | PIK3CDAXLMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | claimed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | claimed |
| EP-2655374-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | Incyte Corporation (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087881-A1 | N-(1-(SUBSTITUTED-PHENYL)ETHYL)-9H-PURIN-6-AMINES AS PI3K INHIBITORS | INCYTE CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |