Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CCR9 | P51686 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.33 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10154231 | 0.78 | GAA (0.46) | KIF11CYP19A1GAASMN1; SMN2TP53 | |
| SCHEMBL2008574 | 0.74 | GAA (0.46) | KIF11CYP19A1GAANPC1RAB9A | |
| SCHEMBL30746425 | 0.74 | GAA (0.46) | KIF11CYP19A1GAANPC1RAB9A | |
| SCHEMBL26916355 | 0.71 | GAA (0.48) | CYP19A1GAASMN1; SMN2TP53MAPT | |
| SCHEMBL9952379 | 0.70 | KIF11 (0.40) | KIF11CYP19A1GAACCR9NPC1 | |
| SCHEMBL31358487 | 0.66 | GAA (0.41) | KIF11CYP19A1GAASMN1; SMN2TP53 | |
| SCHEMBL11955155 | 0.66 | GAA (0.41) | KIF11CYP19A1GAASMN1; SMN2TP53 | |
| SCHEMBL26916918 | 0.66 | SLC22A12 (0.42) | GAANPC1POLB | |
| SCHEMBL805458 | 0.65 | LATS1 (0.40) | KIF11GAANPC1POLBMAPT | |
| SCHEMBL16167559 | 0.65 | KIF11 (0.34) | KIF11NPC1RAB9APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087630-A1 | PYRIDINE AND PYRIMIDINE COMPOUNDS FOR CONTROLLING INVERTEBRATE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |