⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397639 | 1.00 | — | — | |
| SCHEMBL17460346 | 1.00 | — | — | |
| SCHEMBL20513035 | 0.79 | — | — | |
| SCHEMBL436989 | 0.79 | — | — | |
| SCHEMBL23765660 | 0.76 | MEN1 (0.38) | — | |
| SCHEMBL19107454 | 0.76 | MEN1 (0.38) | — | |
| SCHEMBL12775011 | 0.76 | MEN1 (0.38) | — | |
| SCHEMBL2639323 | 0.76 | MEN1 (0.38) | — | |
| SCHEMBL19107453 | 0.76 | MEN1 (0.38) | — | |
| SCHEMBL14745208 | 0.76 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2654772-B1 | CYCLIC CRF ANTAGONIST PEPTIDES | SALK INST BIOLOGICAL STUDIES (US) | 2018-09-26 | — | — | EP | claimed |
| US-9035022-B2 | Cyclic CRF antagonist peptides | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2015-05-19 | — | — | US | claimed |
| US-20140024802-A1 | CYCLIC CRF ANTAGONIST PEPTIDES | SALK INSTITUTE FOR BIOLOGICAL STUDIES | 2014-01-23 | — | — | US | claimed |
| EP-2654772-A2 | CYCLIC CRF ANTAGONIST PEPTIDES | The Salk Institute for Biological Studies (US) | 2013-10-30 | — | — | EP | claimed |
| WO-2012088397-A2 | CYCLIC CRF ANTAGONIST PEPTIDES | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2012-06-28 | — | — | WO | claimed |