SCHEMBL436989

SCHEMBL436989

NCCOCCOC[C]=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20513035 1.00
SCHEMBL999400 0.95
SCHEMBL2780260 0.86 MEN1 (0.32)
SCHEMBL1397639 0.79
SCHEMBL9952284 0.79
SCHEMBL17460346 0.79
SCHEMBL3393452 0.77
SCHEMBL23765660 0.76 MEN1 (0.38)
SCHEMBL19107454 0.76 MEN1 (0.38)
SCHEMBL2639323 0.76 MEN1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 926 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190936-A1 Incretin Analogs and Uses Thereof ELI LILLY AND COMPANY 2024-06-13 US claimed
EP-4199946-B1 CRF2 RECEPTOR AGONISTS AND THEIR USE IN THERAPY SANOFI SA (FR) 2024-06-05 EP claimed
CN-118021978-A GHRH antagonists for use in methods of treating sarcoidosis 迈阿密大学 2024-05-14 CN claimed
WO-2024067662-A1 GLP-1/GCG/GIP TRIPLE-RECEPTOR AGONIST AND USE THEREOF 广东东阳光药业股份有限公司 2024-04-04 WO claimed
EP-4331674-A2 GHRH ANTAGONISTS FOR USE IN A METHOD OF TREATING SARCOIDOSIS University of Miami (US) 2024-03-06 EP claimed
CN-117320740-A GIP/GLP1 dual agonist treatment methods 伊莱利利公司 2023-12-29 CN claimed
US-11851468-B2 Treatment of neurological diseases UNIVERSITY OF LANCASTER (GB) 2023-12-26 US claimed
US-11834486-B2 Incretin analogs and uses thereof ELI LILLY AND COMPANY (US) 2023-12-05 US claimed
US-20230372508-A1 LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES OLIX US, INC. 2023-11-23 US claimed
WO-2023225650-A1 LINKERS COUPLING FUNCTIONAL LIGANDS TO MACROMOLECULES OLIX US, INC. (US) 2023-11-23 WO claimed
EP-1853627-A2 GIP ANALOG AND HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES Amylin Pharmaceuticals, Inc. (US) 2007-11-14 EP claimed
JP-2007525495-A 2007-09-06 JP claimed
EP-1796709-A2 ANALOGS OF SHK TOXIN AND THEIR USES IN SELECTIVE INHIBITION OF KV1.3 POTASSIUM CHANNELS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-06-20 EP claimed
WO-2007022123-A2 HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS, INC. (US) 2007-02-22 WO claimed
US-20060293232-A1 Hybrid polypeptides with selectable properties AMYLIN PHARMACEUTICALS, INC. (US) 2006-12-28 US claimed
EP-1718665-A2 HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES Amylin Pharmaceuticals, Inc. (US) 2006-11-08 EP claimed
WO-2006086769-A2 GIP ANALOG AND HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS, INC. (US) 2006-08-17 WO claimed
US-20060094652-A1 Hybrid polypeptides with selectable properties AMYLIN PHARMACEUTICALS, INC. 2006-05-04 US claimed
WO-2006042151-A2 ANALOGS OF SHK TOXIN AND THEIR USES IN SELECTIVE INHIBITION OF KV1.3 POTASSIUM CHANNELS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2006-04-20 WO claimed
WO-2005077072-A2 HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS, INC. (US) 2005-08-25 WO claimed